Achilles tendon rupture and fluoroquinolones use: report of two cases.

A report of two cases of fluoroquinolones-associated Achilles tendon rupture in two previously-healthy males is presented. Neither of them had any other predisposing condition for this complication. Both were used to strenuous physical activity. No other cause could be found in relation to their traumatic experience. Emphasis is placed on the necessity of identifying this potential and probably unusual complication of these widely-used antimicrobials.