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灵长类染色体的进化

Evolution of primate chromosomes.

作者信息

Miller D A

出版信息

Science. 1977 Dec 16;198(4322):1116-24. doi: 10.1126/science.929190.

Abstract

Human and higher primate chromosomes have been compared by general and regional banding methods, including hybridization in situ. The general banding patterns of the chromosomes of gorilla, chimpanzee, and orangutan, but not gibbon, are similar to those of the human. Preliminary results show that chromosomes with similar banding patterns in different species often carry the same genes. Repetitious DNA's have undergone changes in structure and distribution which are reflected in changes in the regional banding patterns. These studies confirm that the evolutionary distance between the gibbon and the orangutan is relatively great compared to the distance between the orangutan and the other great apes, and suggest that man is more closely related to the gorilla than to the chimpanzee.

摘要

人类和高等灵长类动物的染色体已通过包括原位杂交在内的常规和区域显带方法进行了比较。大猩猩、黑猩猩和猩猩(但不包括长臂猿)染色体的常规显带模式与人类相似。初步结果表明,不同物种中具有相似显带模式的染色体通常携带相同的基因。重复DNA在结构和分布上发生了变化,这反映在区域显带模式的变化中。这些研究证实,与猩猩和其他大型猿类之间的距离相比,长臂猿和猩猩之间的进化距离相对较大,并表明人类与大猩猩的关系比与黑猩猩的关系更密切。

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