A new prion controls fungal cell fusion incompatibility.
作者信息
Wickner R B
机构信息
Laboratory of Biochemistry and Genetics, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Building 8, Room 225, 8 Center Drive MSC 0830, Bethesda, MD 20892-0830, USA.
出版信息
Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10012-4. doi: 10.1073/pnas.94.19.10012.
Abstract
摘要
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The protein product of the het-s heterokaryon incompatibility gene of the fungus Podospora anserina behaves as a prion analog.粪生粪壳菌（Podospora anserina）的het-s异核体不相容基因的蛋白质产物表现为一种朊病毒类似物。
Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9773-8. doi: 10.1073/pnas.94.18.9773.
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The role of PrP in pathogenesis of experimental scrapie.朊蛋白在实验性羊瘙痒病发病机制中的作用。
Cold Spring Harb Symp Quant Biol. 1996;61:511-22.
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In vitro propagation of the prion-like state of yeast Sup35 protein.酵母 Sup35 蛋白朊病毒样状态的体外增殖
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Human TSE disease--viral or protein only?人类传染性海绵状脑病——仅是病毒或仅是蛋白质致病？
Nat Med. 1997 May;3(5):491-2. doi: 10.1038/nm0597-491.
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Transmission of the BSE agent to mice in the absence of detectable abnormal prion protein.在未检测到异常朊病毒蛋白的情况下将牛海绵状脑病病原体传播给小鼠。
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