Said S A, el Gamal M I, van der Werf T
Department of Cardiology, Hospital Streekziekenhuis Midden-Twente, Hengelo, The Netherlands.
Clin Cardiol. 1997 Sep;20(9):748-52. doi: 10.1002/clc.4960200907.
We considered it worthwhile to review the literature of the last decade (1985-1995) to answer the question whether the etiology and the clinical picture of coronary arteriovenous fistulas (CAVFs) have changed. Furthermore, new therapeutic modalities such as percutaneous transcatheter embolization have been developed. We tried to define the place of these techniques in the therapeutic arena. Clinical presentation and management of six patients with eight congenital CAVFs and 76 subjects with 96 congenital and acquire I CAVFs taken from a review of the recent literature are presented. Sixty-three review subjects (78%) were treated medically with one fatal case. Ligation of the fistula was achieved by surgical techniques in 10% of review subjects, while percutaneous transcatheter embolization (PTE) was performed in nine patients (12%). Percutaneous transcatheter embolization techniques are being increasingly used in the treatment of CAVFs. The etiology of CAVFs has a tendency to show alterations toward the acquired pathogenesis. In 64% of the review subjects the fistula was congenital in origin, and in 36% it had an acquired cause. Among the patients of the current review, the clinical presentations were 55% asymptomatic, 34% chest pain (anginal or atypical), and 13% congestive heart failure. The CAVFs of our six patients are all congenital in origin. In the current review, the clinical presentation showed a trend toward increasing chest complaints (34%) compared with the review (10%) published in the mid 1970s. This may be due to a higher mean age, and hence increased concurrent coronary artery disease due to aging compared with the review population of two decades ago.
我们认为回顾过去十年(1985 - 1995年)的文献以回答冠状动脉动静脉瘘(CAVF)的病因和临床表现是否发生变化这一问题是值得的。此外,诸如经皮导管栓塞术等新的治疗方式已得到发展。我们试图明确这些技术在治疗领域中的地位。本文呈现了从近期文献回顾中选取的6例患有8处先天性CAVF的患者以及76例患有96处先天性和后天性CAVF的患者的临床表现及治疗情况。63例回顾对象(78%)接受了药物治疗,其中1例死亡。10%的回顾对象通过外科手术结扎了瘘管,而9例患者(12%)接受了经皮导管栓塞术(PTE)。经皮导管栓塞技术在CAVF治疗中的应用越来越广泛。CAVF的病因有向后天性发病机制转变的趋势。在64%的回顾对象中,瘘管起源于先天性,36%有后天性病因。在本次回顾的患者中,55%无症状,34%有胸痛(典型或非典型心绞痛),13%有充血性心力衰竭。我们6例患者的CAVF均为先天性起源。在本次回顾中,与20世纪70年代中期发表的回顾相比,临床表现显示出胸痛主诉增加的趋势(34%对10%)。这可能是由于平均年龄较高,因此与二十年前的回顾人群相比,因衰老导致的冠状动脉疾病并发率增加。