Ishikawa M, Sakata K, Maki A, Mizuno H, Ishikawa K
Second Department of Internal Medicine, School of Medicine, Kyorin University, Mitaka City, Tokyo, Japan.
Am J Cardiol. 1997 Sep 1;80(5):619-21. doi: 10.1016/s0002-9149(97)00433-5.
Patients (n = 181) with a myocardial infarction, with (n = 20) or without (n = 161) a clearly audible fourth heart sound detected 1 month after the onset of a myocardial infarction, were followed for 56.2 +/- 21.4 months for cardiac events (death, myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass surgery, worsening angina, or heart failure). The present study suggests that a clearly audible fourth heart sound detected 1 month after the onset of myocardial infarction increases the risk of adverse cardiac events.
181例心肌梗死患者，在心肌梗死发病1个月后检测到有（n = 20）或无（n = 161）清晰可闻的第四心音，随访56.2±21.4个月观察心脏事件（死亡、心肌梗死、经皮腔内冠状动脉成形术、冠状动脉旁路移植术、心绞痛恶化或心力衰竭）。本研究表明，心肌梗死发病1个月后检测到清晰可闻的第四心音会增加不良心脏事件的风险。
