Jallon P
Hôpital Cantonal Universitaire, Genève, Suisse.
Rev Neurol (Paris). 1997 Apr;153(3):173-84.
The relations between epilepsy and heart are complex and expressed in two opposite sides. (1) Cardiac arrhythmias may provoke epileptic seizures but these seizures are, in this case, syncopal attacks. Nevertheless, in the past, these clinical features have been individualized as "cardiac epilepsy" or epilepsy in cardiacs. However, true epileptic seizures could be observed in the course of a syncopal attack and a syncope may complicate the issue of an epileptic seizure. (2) On the other hand, epileptic seizures may provoke severe cardiac arrhythmias. The incidence rate of sudden death in patients with epilepsy is estimated to be 1/1000 patients. The exact neural mechanisms in cardiac arrhythmias seizures could explain only some of the sudden unexpected deaths observed in epileptic patients. The role of antiepileptic drugs on cardiac conduction as well as the effects of seizures or status epilepticus on the myocardium are other enigmatic aspects of the relations between epilepsy and heart.
癫痫与心脏之间的关系很复杂，体现在两个相反的方面。（1）心律失常可能引发癫痫发作，但在这种情况下，这些发作属于晕厥发作。然而，过去这些临床特征被个体化地归类为“心源性癫痫”或心脏疾病中的癫痫。不过，在晕厥发作过程中可观察到真正的癫痫发作，而晕厥可能使癫痫发作问题变得复杂。（2）另一方面，癫痫发作可能引发严重的心律失常。癫痫患者的猝死发生率估计为千分之一。心律失常发作的确切神经机制只能解释癫痫患者中观察到的部分意外猝死情况。抗癫痫药物对心脏传导的作用以及癫痫发作或癫痫持续状态对心肌的影响是癫痫与心脏关系中的其他神秘方面。
