Gille M, Ghariani S, Piéret F, Delbecq J, Depré A, Saussu F, de Barsy T
Service de Neurologie, Clinique Sainte-Elisabeth, Bruxelles.
Rev Neurol (Paris). 1997 May;153(4):268-70.
A 44-year-old maniacodepressive woman developed acute encephalopathy due to the association of lithium carbonate and haloperidol. She was treated with lithium salts for many years and the serum level of lithium was within the therapeutic range. The encephalopathy was worsened by hyperthermia, dehydration, and reintroduction of haloperidol, 5 days after the first discontinuation of the neuroleptic. The clinical features were characterized by a persistent cerebellar syndrome, more than one year after the interruption of these medications.
一名44岁的双相情感障碍女性因碳酸锂与氟哌啶醇联用而发生急性脑病。她多年来一直服用锂盐，血清锂水平在治疗范围内。在首次停用抗精神病药物5天后，高热、脱水及重新使用氟哌啶醇使脑病加重。在停用这些药物一年多后，临床特征表现为持续性小脑综合征。
