FitzGerald D B, Cosgrove G R, Ronner S, Jiang H, Buchbinder B R, Belliveau J W, Rosen B R, Benson R R
NMR Center, Charlestown, MA 02129, USA.
AJNR Am J Neuroradiol. 1997 Sep;18(8):1529-39.
To determine the accuracy of functional MR imaging in locating language areas for planning surgical resection.
Intraoperative photographs were digitized and overlaid on functional MR language maps. The sensitivity and specificity of functional MR imaging for identifying language areas were determined for five different language tasks by comparing functional MR areas of language activation with results of electrocortical stimulation. A match was considered to occur if an activated area contacted overlapped, or surrounded a language tag. The borders of the activation areas were extended by 1 and 2 cm to determine whether the number of matches changed. Language and nonlanguage tag matches were tabulated separately.
Sensitivity/specificity for all patients and all language tasks ranged from 81%/53% for areas that touched to 92%/0% for areas separated by 2 cm. Individual language tasks were not as sensitive as a battery of language tasks combined. Location of language areas varied among subjects for a given task and among tasks for a given subject.
Functional MR imaging should be considered a useful presurgical planning tool for mapping cortical language areas, because it is sensitive, it provides increased time for planning before surgery, and it is noninvasive.
确定功能磁共振成像在定位语言区域以规划手术切除方面的准确性。
将术中照片数字化并叠加在功能磁共振语言图谱上。通过将功能磁共振语言激活区域与皮质电刺激结果进行比较，确定了五种不同语言任务中功能磁共振成像识别语言区域的敏感性和特异性。如果激活区域接触、重叠或包围语言标记，则认为存在匹配。将激活区域的边界扩展1厘米和2厘米，以确定匹配数量是否发生变化。分别列出语言和非语言标记匹配情况。
所有患者和所有语言任务的敏感性/特异性范围从接触区域的81%/53%到相隔2厘米区域的92%/0%。单个语言任务不如一组语言任务组合敏感。对于给定任务，语言区域的位置在不同受试者之间有所不同，对于给定受试者，在不同任务之间也有所不同。
功能磁共振成像应被视为一种有用的术前规划工具，用于绘制皮质语言区域，因为它敏感，能在手术前提供更多的规划时间，且是非侵入性的。
