利用磁化传递测量法检测肌萎缩侧索硬化症中的锥体束病变
Detection of pyramidal tract lesions in amyotrophic lateral sclerosis with magnetization-transfer measurements.
作者信息
Kato Y, Matsumura K, Kinosada Y, Narita Y, Kuzuhara S, Nakagawa T
机构信息
Department of Neurology, Mie University School of Medicine, Japan.
出版信息
AJNR Am J Neuroradiol. 1997 Sep;18(8):1541-7.
Abstract
PURPOSE
To determine the presence of small lesions in the pyramidal tract in patients with amyotrophic lateral sclerosis (ALS) by using magnetization-transfer (MT) measurements and MR imaging.
METHODS
MT ratios (MTRs) were measured in the posterior limb of the internal capsule in nine patients with ALS and in nine healthy volunteers.
RESULTS
The mean value of MTRs (%) in patients with ALS was 15.76 +/- 1.48, while that of the control subjects was 19.83 +/- 1.54. The difference was statistically significant.
CONCLUSIONS
MT measurements are useful for detecting abnormalities associated with degeneration of the pyramidal tract in patients with ALS.
摘要
目的
通过使用磁化传递（MT）测量和磁共振成像（MR成像）来确定肌萎缩侧索硬化症（ALS）患者锥体束中微小病变的存在情况。
方法
对9例ALS患者和9名健康志愿者的内囊后肢进行MT比率（MTR）测量。
结果
ALS患者的MTRs（%）平均值为15.76±1.48，而对照组受试者的该值为19.83±1.54。差异具有统计学意义。
结论
MT测量有助于检测ALS患者锥体束退变相关的异常情况。
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