Fugelstad A, Annell A, Rajs J, Agren G
Psychiatric Clinic for Alcohol and Drug Dependence, Karolinska Institute, St Görans Hospital, Stockholm, Sweden.
Acta Psychiatr Scand. 1997 Sep;96(3):169-75. doi: 10.1111/j.1600-0447.1997.tb10147.x.
A cohort of 1640 hospitalized drug addicts was studied over an 8-year period, and consisted of 678 heroin users, 578 amphetamine users and 384 users of other drugs. In total, 234 addicts were HIV-positive, most of them heroin users. During the observation period, 214 deaths occurred in the cohort. The total mortality was 2.2% annually. Death linked to injection of heroin was the main cause of death not only among heroin users but also among subjects classified as users of amphetamines or other drugs. During the observation period, a total of 222 addicts (115 of whom were HIV-positive) entered the methadone programme. No deaths occurred among the HIV-negative subjects who were participating in the methadone programme. A total of 15 HIV-positive subjects died while taking part in the programme--13 of these subjects from natural causes (mostly HIV/AIDS).
对一组1640名住院吸毒者进行了为期8年的研究，其中包括678名海洛因使用者、578名苯丙胺使用者和384名使用其他毒品的人。总共有234名吸毒者艾滋病毒呈阳性，其中大多数是海洛因使用者。在观察期内，该队列中有214人死亡。总死亡率为每年2.2%。与注射海洛因相关的死亡不仅是海洛因使用者的主要死因，也是被归类为苯丙胺或其他毒品使用者的主要死因。在观察期内，共有222名吸毒者（其中115名艾滋病毒呈阳性）进入美沙酮治疗项目。参与美沙酮治疗项目的艾滋病毒阴性受试者中没有死亡。共有15名艾滋病毒呈阳性的受试者在参与该项目期间死亡——其中13名受试者死于自然原因（主要是艾滋病毒/艾滋病）。
