Queuche F
AUPELF-UREF, Bureau Asie du Sud-Est, Lê Thanh Tông, Hanoi, Viet Nam.
Sante. 1997 May-Jun;7(3):155-9.
We studied 155 patients with chronic pulmonary disease from a mountainous area in north-west Vietnam, in March, 1993. Sputum was collected from patients and examined for the presence of Paragonimus eggs using a light microscope. Forty four of the patients (approximately 28%) were diagnosed with and treated for human paragonimiasis. Forty two of these cases were purely pleural-pulmonary forms whereas the remaining two cases also involved problems with the central nervous system. Most of the patients had eaten freshwater crabs (Ranguna luangprabangensis) which had been insufficiently cooked. This appears to be the main source of infection as these crustaceans are often highly contaminated with metacercariae. Most of the patients were children (aged 11 +/- 5 years) and male (30 of the 44). Sputum samples were also collected from 225 healthy people from the same area during the period March 1993 to April 1996. The samples were examined using a light microscope and 11 (approximately 5%) were found to contain Paragonimus eggs. A number of animals were also tested. Three pet dogs (of 14 tested), 2 wild dogs (of 2 tested) and 2 domestic pigs (of 15 tested) were found to be infected with the fluke. This is the first report of an area with endemic paragonimiasis in Vietnam. Human infections probably also occur in other areas. They are a threat to public health and may be confused with tuberculosis.
1993年3月，我们对来自越南北部山区的155名慢性肺病患者进行了研究。从患者身上采集痰液，用光学显微镜检查是否存在肺吸虫卵。其中44名患者（约28%）被诊断为人肺吸虫病并接受了治疗。其中42例为单纯胸膜 - 肺型，其余2例还涉及中枢神经系统问题。大多数患者食用过未充分煮熟的淡水蟹（兰氏溪蟹）。由于这些甲壳类动物常常被尾蚴高度污染，这似乎是主要的感染源。大多数患者为儿童（年龄11±5岁），且以男性居多（44例中有30例）。在1993年3月至1996年4月期间，还从同一地区的225名健康人身上采集了痰液样本。样本经光学显微镜检查，发现11人（约5%）的样本中含有肺吸虫卵。还对一些动物进行了检测。在14只受试宠物狗中有3只、2只受试野狗中的2只以及15只受试家猪中的2只被发现感染了吸虫。这是越南地方性肺吸虫病流行地区的首次报告。人类感染可能在其他地区也有发生。它们对公众健康构成威胁，且可能与结核病相混淆。
