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[体力活动对心源性猝死发生率的影响。柏林-赖尼肯多夫和柏林-施潘道人群研究]

[Effect of physical activity on incidence of sudden cardiac death. Study of the Berlin-Reinickendorf and Berlin-Spandau population].

作者信息

Bartels R, Menges M, Thimme W

机构信息

I. Innere Abteilung, Humboldt-Krankenhaus Berlin.

出版信息

Med Klin (Munich). 1997 Jun 15;92(6):319-25. doi: 10.1007/BF03044770.

Abstract

AIM

Our investigation examined the influence of regular physical activity and sudden extrenious situations on the incidence of sudden cardiac death (scd) in two different Berlin districts with a total population of 219,251 in the examined age-groups.

PATIENTS AND METHOD

All cases of scd which occurred outside of the hospital and were documented as been induced from ventricular fibrillation were examined over a time period of 18 months. For each case the amount of and the intensity of their regular physical activity was determined. In addition the stress of the sudden extrenious situations was survived. The study population was divided into various groups depending upon their level of regular physical activity. For each group the incidence of sudden cardiac death was determined. Then the relative risk for scd during strenuous activity compared to inactivity was determined for each group. The influence of preexisting disease was calculated.

RESULTS

77 patients with scd induced from ventricular fibrillation were included in our study. In the sedentary group we found an incidence of 4.69 scd per 10(5) person-years, in the group with a low level of regular physical activity we found an incidence of 4.25, in the group with a middle level of regular physical activity an incidence of 2.63 and in the most active group 0.92 scd per 10(5) person-years. We found the relative risk for scd during highly strenuous activity compared with inactivity to be 150 in the sedentary group as opposed to 4.0 in the most active group. The preexisting illness status of the case-groups had no influence on the outcome.

CONCLUSIONS

The results show that the risk of scd for all persons regardless of their levels of regular physical activity and their preillness status is higher during strenuous activity than during inactivity. The increase of the risk for scd during activity is the highest for persons with sedentary lifestyles, whereas the risk increase for persons with active lifestyles is minimal. The protective effect of regular physical activity for scd by far exceeds the risk increase of the actual strenuous situation.

摘要

目的

我们的调查研究了规律体育活动和突发外部情况对柏林两个不同城区突发心脏性猝死(SCD)发生率的影响,研究对象为所考察年龄组中总计219,251名人口。

患者与方法

对所有发生在院外且记录为由心室颤动诱发的SCD病例进行了为期18个月的调查。针对每个病例,确定其规律体育活动的量和强度。此外,评估突发外部情况所带来的压力。根据规律体育活动水平,将研究人群分为不同组。确定每组突发心脏性猝死的发生率。然后确定每组在剧烈活动期间与不活动相比SCD的相对风险。计算既往疾病的影响。

结果

我们的研究纳入了77例由心室颤动诱发SCD的患者。在久坐不动组中,我们发现每10⁵人年SCD发生率为4.69,规律体育活动水平低的组中发生率为4.25,规律体育活动水平中等的组中发生率为2.63,而最活跃组中每10⁵人年SCD发生率为0.92。我们发现,久坐不动组在剧烈活动期间与不活动相比SCD的相对风险为150,而最活跃组为4.0。病例组的既往疾病状况对结果无影响。

结论

结果表明,无论规律体育活动水平和疾病前状态如何,所有人在剧烈活动期间发生SCD的风险均高于不活动期间。久坐不动生活方式的人在活动期间SCD风险增加最高,而积极生活方式的人风险增加最小。规律体育活动对SCD的保护作用远远超过实际剧烈情况带来的风险增加。

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