Pedersen G, Dalseg A M, Brynskov J, Bendtzen K
Medicinsk afdeling C, Amtssygehuset i Herlev.
Ugeskr Laeger. 1997 Aug 18;159(34):5077-84.
Adhesion molecules participate in a broad variety of biological processes, i.e. tumour progression and inflammation, through their involvement in cell-to-cell interactions and immunoinflammatory cell migration. This review describes the basic properties of adhesion molecules with reference to inflammatory bowel disease and colorectal carcinoma. Future therapeutic approaches in inflammatory and malignant disorders may include development of principles targeting adhesion molecules.
黏附分子通过参与细胞间相互作用和免疫炎症细胞迁移,参与多种生物学过程,即肿瘤进展和炎症。本综述参照炎症性肠病和结直肠癌描述了黏附分子的基本特性。炎症和恶性疾病未来的治疗方法可能包括制定针对黏附分子的原则。