Tyran B, Lisowski J
Arch Immunol Ther Exp (Warsz). 1979;27(4):487-98.
Comparative studies of physiocochemical properties of ovine and bovine serum and colostral IgM are described. Serologic properties, molecular weight, amino acid composition, carbohydrate content, peptide maps, heterogeneity, and ORD and CD spectra were compared. Colostral IgM have additional antigenic determinants, higher carbohydrate content, lower heterogeneity, and higher content of beta-structure. Different amino acid composition and different peptide maps of serum and colostral IgM were shown. The results obtained suggest that ovine and bovine colostral IgM immunoglobulins may be a mixed population of molecules locally synthesized and transferred from the serum.
本文描述了绵羊和牛血清及初乳中IgM的理化性质的比较研究。比较了血清学性质、分子量、氨基酸组成、碳水化合物含量、肽图、异质性以及ORD和CD光谱。初乳IgM具有额外的抗原决定簇、更高的碳水化合物含量、更低的异质性以及更高的β结构含量。血清和初乳IgM显示出不同的氨基酸组成和不同的肽图。所得结果表明，绵羊和牛初乳中的IgM免疫球蛋白可能是局部合成并从血清转移而来的混合分子群体。
