Teichman J M, Nielsen-Omeis B J, McIver B D
Division of Urology, University of Texas Health Science Center, San Antonio 78284-7845, USA.
Tech Urol. 1997 Summer;3(2):65-8.
Interstitial cystitis (IC) is a poorly understood syndrome. Patients with pelvic pain, urgency, frequency, and/or dysuria may pose a diagnostic dilemma. They may have bladder-related symptoms or they may have nonbladder related symptoms. It is beneficial for the urologist to distinguish between these patients. This study outlined a modified urodynamics test to discriminate between bladder-related and nonbladder-related patients. Consecutive IC patients (bladder-related and nonbladder-related patients) and stress incontinent controls underwent modified urodynamics. Testing consisted of an epithelial leak test, a filling cystometrogram, bladder emptying and instilling lidocaine intravesically, and repeat cystometrogram after bladder emptying. The epithelial leak test and lidocaine test predict reliably if a patient has bladder-related or nonbladder-related symptoms. Modified urodynamics permits a logical stratification of IC patients, and may predict treatment response.
间质性膀胱炎（IC）是一种了解甚少的综合征。患有盆腔疼痛、尿急、尿频和/或排尿困难的患者可能会带来诊断难题。他们可能有膀胱相关症状，也可能有非膀胱相关症状。对泌尿科医生来说，区分这些患者是有益的。本研究概述了一种改良的尿动力学测试，以区分膀胱相关和非膀胱相关患者。连续的间质性膀胱炎患者（膀胱相关和非膀胱相关患者）以及压力性尿失禁对照组接受了改良尿动力学检查。测试包括上皮渗漏试验、充盈性膀胱测压、膀胱排空和膀胱内注入利多卡因，以及膀胱排空后的重复膀胱测压。上皮渗漏试验和利多卡因试验能够可靠地预测患者是否有膀胱相关或非膀胱相关症状。改良尿动力学可对间质性膀胱炎患者进行合理分层，并可能预测治疗反应。
