• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

论遗传密码的起源。

On the origin of the genetic code.

作者信息

Di Giulio M

机构信息

International Institute of Genetics and Biophysics, CNR, Napoli, Italy.

出版信息

J Theor Biol. 1997 Aug 21;187(4):573-81. doi: 10.1006/jtbi.1996.0390.

DOI:10.1006/jtbi.1996.0390
PMID:9299300
Abstract

The main theories which have been suggested to explain the origin of genetic code organization are discussed. The coevolution theory, which considers the genetic code as a map of the biosynthetic relationships between amino acids, seems to be based on a mechanism that links it closely to certain stages of the origin of metabolism, which makes it preferable to other theories proposed as explanations of genetic code origin. Relationships, incompatibilities and compromises between the various theories are highlighted and these seem to indicate a certain lack of clarity in this field of research.

摘要

本文讨论了为解释遗传密码组织起源而提出的主要理论。共进化理论将遗传密码视为氨基酸之间生物合成关系的图谱,该理论似乎基于一种将其与代谢起源的某些阶段紧密联系起来的机制,这使得它比其他作为遗传密码起源解释而提出的理论更具优势。文中强调了各种理论之间的关系、不相容性和折衷之处,这些似乎表明该研究领域存在一定的模糊性。

相似文献

1
On the origin of the genetic code.论遗传密码的起源。
J Theor Biol. 1997 Aug 21;187(4):573-81. doi: 10.1006/jtbi.1996.0390.
2
The origin of the genetic code: theories and their relationships, a review.遗传密码的起源:理论及其关系,一篇综述
Biosystems. 2005 May;80(2):175-84. doi: 10.1016/j.biosystems.2004.11.005. Epub 2004 Dec 25.
3
Reflections on the origin of the genetic code: a hypothesis.关于遗传密码起源的思考:一种假说。
J Theor Biol. 1998 Mar 21;191(2):191-6. doi: 10.1006/jtbi.1997.0580.
4
The non-universality of the genetic code: the universal ancestor was a progenote.遗传密码的非通用性:普遍共同祖先为原基因组生物。
J Theor Biol. 2001 Apr 7;209(3):345-9. doi: 10.1006/jtbi.2001.2271.
5
The level and landscape of optimization in the origin of the genetic code.遗传密码起源中的优化水平与格局。
J Mol Evol. 2001 Apr;52(4):372-82. doi: 10.1007/s002390010167.
6
A blind empiricism against the coevolution theory of the origin of the genetic code.对遗传密码起源的共同进化理论的盲目经验主义。
J Mol Evol. 2001 Dec;53(6):724-32. doi: 10.1007/s002390010259.
7
The close relationship between the biosynthetic families of amino acids and the organisation of the genetic code.氨基酸的生物合成家族与遗传密码的组织之间的密切关系。
Gene. 2009 Apr 15;435(1-2):9-12. doi: 10.1016/j.gene.2008.12.018. Epub 2009 Jan 14.
8
The lack of foundation in the mechanism on which are based the physico-chemical theories for the origin of the genetic code is counterposed to the credible and natural mechanism suggested by the coevolution theory.物理化学理论中关于遗传密码起源所依据的机制缺乏基础,这与协同进化理论所提出的可信且自然的机制形成了对比。
J Theor Biol. 2016 Jun 21;399:134-40. doi: 10.1016/j.jtbi.2016.04.005. Epub 2016 Apr 8.
9
The aminoacyl-tRNA synthetases had only a marginal role in the origin of the organization of the genetic code: Evidence in favor of the coevolution theory.氨酰-tRNA合成酶在遗传密码组织起源中仅起次要作用:支持共同进化理论的证据。
J Theor Biol. 2017 Nov 7;432:14-24. doi: 10.1016/j.jtbi.2017.08.005. Epub 2017 Aug 9.
10
Some pungent arguments against the physico-chemical theories of the origin of the genetic code and corroborating the coevolution theory.一些针对遗传密码起源的物理化学理论的尖锐论点,并支持协同进化理论。
J Theor Biol. 2017 Feb 7;414:1-4. doi: 10.1016/j.jtbi.2016.11.014. Epub 2016 Nov 19.

引用本文的文献

1
The optimality of the standard genetic code assessed by an eight-objective evolutionary algorithm.用 8 目标进化算法评估标准遗传密码的最优性。
BMC Evol Biol. 2018 Dec 13;18(1):192. doi: 10.1186/s12862-018-1304-0.
2
Optimization of the standard genetic code according to three codon positions using an evolutionary algorithm.根据三个密码子位置使用进化算法对标准遗传密码进行优化。
PLoS One. 2018 Aug 9;13(8):e0201715. doi: 10.1371/journal.pone.0201715. eCollection 2018.
3
Genetic Code Optimization for Cotranslational Protein Folding: Codon Directional Asymmetry Correlates with Antiparallel Betasheets, tRNA Synthetase Classes.
共翻译蛋白质折叠的遗传密码优化:密码子方向不对称与反平行β折叠、tRNA合成酶类别相关。
Comput Struct Biotechnol J. 2017 Aug 12;15:412-424. doi: 10.1016/j.csbj.2017.08.001. eCollection 2017.
4
An Autotrophic Origin for the Coded Amino Acids is Concordant with the Coevolution Theory of the Genetic Code.编码氨基酸的自养起源与遗传密码的共同进化理论相一致。
J Mol Evol. 2016 Oct;83(3-4):93-96. doi: 10.1007/s00239-016-9760-x. Epub 2016 Oct 14.
5
The origin of the genetic code: matter of metabolism or physicochemical determinism?遗传密码的起源:新陈代谢问题还是物理化学决定论?
J Mol Evol. 2013 Oct;77(4):131-3. doi: 10.1007/s00239-013-9593-9. Epub 2013 Oct 26.
6
Amino acid homochirality may be linked to the origin of phosphate-based life.氨基酸手性可能与基于磷酸盐的生命起源有关。
J Mol Evol. 2010 Jun;70(6):572-82. doi: 10.1007/s00239-010-9353-z. Epub 2010 May 27.
7
RNA relics and origin of life.RNA 遗迹与生命起源。
Int J Mol Sci. 2009 Jul 31;10(8):3420-3441. doi: 10.3390/ijms10083420.
8
Revisiting the operational RNA code for amino acids: Ensemble attributes and their implications.重新审视氨基酸的操作 RNA 密码:集合属性及其意义。
RNA. 2010 Jan;16(1):141-53. doi: 10.1261/rna.1745910. Epub 2009 Dec 1.
9
An extension of the coevolution theory of the origin of the genetic code.遗传密码起源的共同进化理论的扩展。
Biol Direct. 2008 Sep 5;3:37. doi: 10.1186/1745-6150-3-37.
10
Codon usage bias and mutation constraints reduce the level of error minimization of the genetic code.密码子使用偏好和突变限制降低了遗传密码的错误最小化水平。
J Mol Evol. 2004 Aug;59(2):258-66. doi: 10.1007/s00239-004-2620-0.