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粪便形态量表作为肠道转运时间的有用指南。

Stool form scale as a useful guide to intestinal transit time.

作者信息

Lewis S J, Heaton K W

机构信息

University Dept. of Medicine, Bristol Royal Infirmary, UK.

出版信息

Scand J Gastroenterol. 1997 Sep;32(9):920-4. doi: 10.3109/00365529709011203.

Abstract

BACKGROUND

Stool form scales are a simple method of assessing intestinal transit rate but are not widely used in clinical practice or research, possibly because of the lack of evidence that they are responsive to changes in transit time. We set out to assess the responsiveness of the Bristol stool form scale to change in transit time.

METHODS

Sixty-six volunteers had their whole-gut transit time (WGTT) measured with radiopaque marker pellets and their stools weighed, and they kept a diary of their stool form on a 7-point scale and of their defecatory frequency. WGTT was then altered with senna and loperamide, and the measurements were repeated.

RESULTS

The base-line WGTT measurements correlated with defecatory frequency (r = 0.35, P = 0.005) and with stool output (r = -0.41, P = 0.001) but best with stool form (r = -0.54, P < 0.001). When the volunteers took senna (n = 44), the WGTT decreased, whereas defecatory frequency, stool form score, and stool output increased (all, P < 0.001). With loperamide (n = 43) all measurements changed in the opposite direction. Change in WGTT from base line correlated with change in defecatory frequency (r = 0.41, P < 0.001) and with change in stool output (n = -0.54, P < 0.001) but best with change in stool form (r = -0.65, P < 0.001).

CONCLUSIONS

This study has shown that a stool form scale can be used to monitor change in intestinal function. Such scales have utility in both clinical practice and research.

摘要

背景

粪便形态量表是评估肠道转运速率的一种简单方法,但在临床实践或研究中未得到广泛应用,可能是因为缺乏证据表明它们对转运时间的变化有反应。我们旨在评估布里斯托粪便形态量表对转运时间变化的反应性。

方法

66名志愿者通过不透X线的标记物测量其全肠道转运时间(WGTT),并对粪便称重,他们用7分制记录粪便形态日记及排便频率。然后用番泻叶和洛哌丁胺改变WGTT,并重复测量。

结果

基线WGTT测量值与排便频率(r = 0.35,P = 0.005)和粪便排出量(r = -0.41,P = 0.001)相关,但与粪便形态相关性最佳(r = -0.54,P < 0.001)。当志愿者服用番泻叶时(n = 44),WGTT缩短,而排便频率、粪便形态评分和粪便排出量增加(均P < 0.001)。服用洛哌丁胺时(n = 43),所有测量值均朝相反方向变化。WGTT相对于基线的变化与排便频率的变化(r = 0.41,P < 0.001)和粪便排出量的变化(n = -0.54,P < 0.001)相关,但与粪便形态的变化相关性最佳(r = -

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