Uchinuma E, Shioya N
Department of Plastic and Reconstructive Surgery, Kitasato University, School of Medicine, Kanagawa, Japan.
Scand J Plast Reconstr Surg Hand Surg. 1997 Sep;31(3):239-43. doi: 10.3109/02844319709051537.
The validity of Seifert's hypothesis about growth pattern of adenolymphomas has been evaluated in three of five patients with adenolymphomas of the parotid gland, who at the time of a parotidectomy, were found to have multiple unilateral adenolymphomas in the intraglandular lymph nodes. This evaluation, which was based on assessing the epithelial: lymphoid tissue ratio in excised adenolymphomas and the growth in tumor size, showed that there was no association between the histological changes in the epithelial:lymphoid tissue and the tumor size. Adenolymphomas seem to have no consistent growth pattern and develop independently. However, as multiple tumors were detected histopathologically in lymph nodes as small as 5 mm in diameter the importance of a detailed examination of patients with adenolymphomas is stressed, so that other tumours are not overlooked.
在五例腮腺腺淋巴瘤患者中，有三例在腮腺切除术时被发现腺体内淋巴结存在多个单侧腺淋巴瘤，据此对赛弗特关于腺淋巴瘤生长模式的假说进行了评估。该评估基于对切除的腺淋巴瘤上皮与淋巴组织比例以及肿瘤大小增长情况的评估，结果显示上皮与淋巴组织的组织学变化和肿瘤大小之间并无关联。腺淋巴瘤似乎没有一致的生长模式，而是独立发展。然而，由于在直径小至5毫米的淋巴结中经组织病理学检测发现了多个肿瘤，因此强调对腺淋巴瘤患者进行详细检查的重要性，以免忽略其他肿瘤。
