Sauer S, Schellenberg R, Hofmann H C, Dimpfel W
Pro Science Private Research Institute GmbH, med. Forschung und Entwicklung, Kurt-Schumacher-Str. 9, Linden D-35440, Germany.
Eur J Med Res. 1997 Sep 29;2(9):367-76.
A highly sensitive quantitative-topographical EEG was used in order to define first steps in an objective classification of migraine. A 17-channel quantitative EEG was recorded in 30 patients suffering from migraine with or without aura during the painfree interval. These EEG s were compared to EEGs of age related healthy norm groups using a new statistical tool called the Aberration Index. A focal aberration in the area of pain was detected in 26 out of the 30 patients mostly due to an increase of alpha1 EEG power (23 patients). Alpha2 or theta power were also increased in several patients. Furthermore, a decrease in alpha power neighbouring the focus was found in 18 patients and a contralateral reduction of alpha power was seen in 16 patients. No difference was detected between migraine with aura and migraine without aura.
为了确定偏头痛客观分类的初步步骤，使用了一种高度敏感的定量地形图脑电图。在30例有无先兆偏头痛患者的无痛间期记录了17通道定量脑电图。使用一种名为像差指数的新统计工具，将这些脑电图与年龄相关的健康正常组的脑电图进行比较。30例患者中有26例在疼痛区域检测到局灶性像差，主要是由于α1脑电图功率增加（23例患者）。几名患者的α2或θ功率也增加。此外，18例患者在病灶附近发现α功率降低，16例患者对侧α功率降低。有先兆偏头痛和无先兆偏头痛之间未检测到差异。
