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丙型肝炎组织学活性指数(HAI)及评分系统的形态学研究

A morphological study of histological activity index (HAI) and scoring system in hepatitis-C.

作者信息

Mushtaq S, Muzaffar M, Khadim M T, Tariq W Z, Mamoon N

机构信息

Armed Forces Institute of Pathology, Rawalpindi.

出版信息

J Pak Med Assoc. 1997 Jun;47(6):162-5.

PMID:9301169
Abstract

A retrospective morphological study of 25 cases of serologically positive chronic hepatitis C was carried out. Paraffin embedded sections were stained with haematoxylin, eosin and Gomori reticulin stains. The histological features were scored according to both Knodell and Scheuer systems. The results of Knodell showed 32% cases scored between 4-8 and 48% between 9-12. Cases of conventional category of chronic persistent hepatitis scored between 1-3 and chronic active hepatitis score ranged between 4-12. The scoring systems provide a good guideline for management/selection of cases for interferone therapy and subsequent evaluation and assessment of the cases.

摘要

对25例血清学阳性的慢性丙型肝炎患者进行了回顾性形态学研究。石蜡包埋切片用苏木精、伊红和Gomori网状纤维染色。根据Knodell和Scheuer系统对组织学特征进行评分。Knodell评分结果显示,32%的病例评分为4-8分,48%的病例评分为9-12分。传统分类的慢性持续性肝炎病例评分为1-3分,慢性活动性肝炎病例评分在4-12分之间。这些评分系统为干扰素治疗病例的管理/选择以及随后对病例的评估提供了良好的指导。

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