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慢性淋巴细胞白血病与骨髓增生异常综合征的同时诊断

Concurrent diagnosis of chronic lymphocytic leukemia and myelodysplastic syndrome.

作者信息

Sylvester L S, Nowell P C, Bonner H, Moreau L, Moore J S

机构信息

Pottstown Memorial Medical Center, Pennsylvania, USA.

出版信息

Leuk Res. 1997 Jul;21(7):619-21. doi: 10.1016/s0145-2126(97)00017-9.

DOI:10.1016/s0145-2126(97)00017-9
PMID:9301682
Abstract

An elderly patient is described with concurrent presentation of chronic lymphocytic leukemia and myelodysplastic syndrome, documented by clinical and hematological findings, flow cytometry and cytogenetics. The chromosome data suggested that these disorders developed as separate clones from two different hematopoietic precursor cells in this patient.

摘要

描述了一名老年患者,其同时出现慢性淋巴细胞白血病和骨髓增生异常综合征,有临床和血液学检查结果、流式细胞术及细胞遗传学检查结果为证。染色体数据表明,在该患者中,这些病症是由两个不同造血前体细胞的独立克隆发展而来。

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Concurrent diagnosis of chronic lymphocytic leukemia and myelodysplastic syndrome.慢性淋巴细胞白血病与骨髓增生异常综合征的同时诊断
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Evaluation of trisomy 12 by fluorescence in situ hybridization in peripheral blood, bone marrow and lymph nodes of patients with B-cell chronic lymphocytic leukemia.采用荧光原位杂交技术对B细胞慢性淋巴细胞白血病患者外周血、骨髓和淋巴结中的12号三体进行评估。
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引用本文的文献

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Multi Cytogenetic Changes in a Patient as Co-Existing MDS and CLL Progresses.一名同时患有骨髓增生异常综合征(MDS)和慢性淋巴细胞白血病(CLL)的患者随着病情进展出现多种细胞遗传学改变。
Onco Targets Ther. 2021 Jan 8;14:177-186. doi: 10.2147/OTT.S281800. eCollection 2021.
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Association of myelodysplastic syndrome with CD5+, CD23+ monoclonal B-cell lymphocytosis.骨髓增生异常综合征与CD5+、CD23+单克隆B细胞淋巴细胞增多症的关联。
Clinics (Sao Paulo). 2012 Dec;67(12):1487-91. doi: 10.6061/clinics/2012(12)22.
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Allogeneic hematopoietic cell transplantation in patients with myelodysplastic syndrome and concurrent lymphoid malignancy.
骨髓增生异常综合征合并淋巴系恶性肿瘤患者的异基因造血细胞移植
Bone Marrow Transplant. 2012 Jun;47(6):804-9. doi: 10.1038/bmt.2011.180. Epub 2011 Sep 12.