Orime Y, Hasegawa T, Kitamura S, Ohira M, Shindo S, Shiono M, Harada Y, Sezai Y
Rinsho Kyobu Geka. 1989 Jun;9(3):246-51.
The cases multiple organ failure (MOF) which occurred post-operatively following open heart surgery in adults were studied on a pre and post-operative hemodynamics. Post-operative low cardiac output syndrome (LOS) was thought to result in decreased renal and hepatic perfusion with subsequent ischemic damage to these organs. Therefore, to management MOF, we have to prevent post-operative LOS, for example, administration of cathecholamine and vasodilator, and early clinical application of IABP and ventricular assist device (VAD). In a post-operative hemodynamics, the cases of severe right ventricular failure tend to have more protracted MOF. It was though that MOF could be minimized with shortened cardiopulmonary bypass duration, and early application of assisted circulation.
对成人心脏直视手术后发生的多器官功能衰竭(MOF)病例进行了术前和术后血流动力学研究。术后低心排血量综合征(LOS)被认为会导致肾和肝灌注减少,继而对这些器官造成缺血性损伤。因此,为了治疗MOF,我们必须预防术后LOS,例如使用儿茶酚胺和血管扩张剂,以及早期临床应用主动脉内球囊反搏(IABP)和心室辅助装置(VAD)。在术后血流动力学方面,严重右心室衰竭的病例往往有更持久的MOF。人们认为,缩短体外循环时间和早期应用辅助循环可以将MOF降至最低。