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[胸心血管外科手术后伴发器官功能衰竭的机械器官支持治疗]

[The treatment of accompanied organ failure after thoracic and cardiovascular surgery with mechanical organ-supports].

作者信息

Tsukamoto M, Kimura H, Sumita S, Ujike Y, Kaneko M, Komatsu S

出版信息

Rinsho Kyobu Geka. 1989 Oct;9(5):472-7.

PMID:9301959
Abstract

Five hundred and thirty-three patients have been treated after thoracic and cardiovascular surgery in our ICU during the last four years. Cardiac failure was shown in 150 cases, respiratory failure in 132 cases, renal failure in 76 cases, and hepatic failure in 84 cases. The appropriate mechanical organ-supports (MOS) were applied in the following cases: intra-aortic balloon pumping (IABP) in 48 cases, veno-arterial bypass (VAB) in 18 cases, left ventricular assist device (LVAD) in 1 case, respirator in 132 cases, continuous hemofiltration (CHF) in 44 cases, hemodialysis (HD) in 13 cases, peritoneal dialysis (PD) in 21 cases, Continuous intensive peritoneal dialysis (CIPD) in 7 cases, and plasma exchange (PEx) in 22 cases. The results of MOS6 which required exocorporeal circulation were not satisfactory, especially CHF (mortality rate 75.0%), HD (76.9%), and VAB (100%). Though, the results of IABP (35.4%) and CIPD (14.3%) were significantly better. The main cause of early death (within 6 post-operative days) was low output syndrome (LOS) (63.6%). However, that of late death (beyond 14 post-operative days) was sepsis (66.7%). Therefore, it is important for the survival of these patients to control LOS during the early post operative period and then to concentrate on the prevention of infection.

摘要

在过去四年中,我们的重症监护病房(ICU)对533例胸心外科手术后的患者进行了治疗。其中150例出现心力衰竭,132例出现呼吸衰竭,76例出现肾衰竭,84例出现肝衰竭。在以下情况应用了适当的机械器官支持(MOS):48例应用主动脉内球囊反搏(IABP),18例应用静脉-动脉体外膜肺氧合(VAB),1例应用左心室辅助装置(LVAD),132例应用呼吸机,44例应用持续血液滤过(CHF),13例应用血液透析(HD),21例应用腹膜透析(PD),7例应用持续强化腹膜透析(CIPD),22例应用血浆置换(PEx)。需要体外循环的MOS的结果并不理想,尤其是CHF(死亡率75.0%)、HD(76.9%)和VAB(100%)。不过,IABP(35.4%)和CIPD(14.3%)的结果明显更好。早期死亡(术后6天内)的主要原因是低心排血量综合征(LOS)(63.6%)。然而,晚期死亡(术后14天以后)的主要原因是脓毒症(66.7%)。因此,对于这些患者的生存而言,在术后早期控制LOS并随后着重预防感染很重要。

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