Sutmoller F, de Souza C T, Monteiro J C, Penna T
Hospital Evandro Chagas, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil.
Mem Inst Oswaldo Cruz. 1997 Jan-Feb;92(1):39-46. doi: 10.1590/s0074-02761997000100009.
The initial effort of the Brazilian Ministry of Health to be an active partner in the world effort in the preparation of future accurate human immune deficiency virus (HIV) efficacy trials was the establishment of a multi-centered cohort of homosexual and bisexual men. An open cohort was established to determine the HIV incidence and the socio-behavioral aspects involved in Rio de Janeiro. A total of 318 potential participants, originated from multiple sources (health units, public information, snowball recruitment), were screened and recruitment became effective through the direct involvement of target communities (with the support of Non Governmental Organizations) and the population. Among this group, seropositivity for sexually transmitted diseases was high with 23, 32 and 46% for HIV, syphilis and hepatitis B, respectively. The socio-demographic data from the first 200 participants of this HIV negative cohort suggests that the cohort volunteers are an appropriate sample of the general male population of the State of Rio de Janeiro.
巴西卫生部为积极参与全球为未来准确开展人类免疫缺陷病毒(HIV)疗效试验所做的努力,最初采取的举措是建立一个由男同性恋者和双性恋男性组成的多中心队列。在里约热内卢设立了一个开放队列,以确定HIV发病率以及相关的社会行为因素。共有318名潜在参与者,他们来自多个渠道(卫生单位、公共宣传、滚雪球式招募),经过筛选,在目标社区(在非政府组织的支持下)和民众的直接参与下,招募工作得以顺利开展。在这一群体中,性传播疾病的血清阳性率很高,HIV、梅毒和乙肝的血清阳性率分别为23%、32%和46%。对这个HIV阴性队列中最初200名参与者的社会人口学数据分析表明,该队列的志愿者是里约热内卢州男性总体人群的一个合适样本。