• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在双向腔肺吻合模型中对不同程度和形状的肺动脉狭窄进行计算性瞬态模拟。

Computational transient simulations with varying degree and shape of pulmonic stenosis in models of the bidirectional cavopulmonary anastomosis.

作者信息

Migliavacca F, Dubini G, Pietrabissa R, de Leval M R

机构信息

Dipartimento di Bioingegneria, Politecnico di Milano, Italy.

出版信息

Med Eng Phys. 1997 Jun;19(4):394-403. doi: 10.1016/s1350-4533(96)00070-7.

DOI:10.1016/s1350-4533(96)00070-7
PMID:9302681
Abstract

The bidirectional cavopulmonary anastomosis is a surgical technique utilized to treat severe congenital malformations of the right part of the heart. It is obtained by anastomosing the superior vena cava to the superior aspect of the undivided right pulmonary artery. Transient simulations with a three-dimensional model of the bidirectional cavopulmonary anastomosis were carried out to evaluate the haemodynamics of different types of pulmonic stenosis (shape and severity of the obstruction). Models with a tunnel-like (supravalvar) or discrete (valvar) pulmonic stenosis with different values of reduction of cross-sectional area (60 and 75%) were investigated and compared to a model without stenosis. Calculations were based on a finite element method analysis. The results showed that a tighter stenosis can lead to a blood volume flow to the left lung reaching 70% of the total pulmonary flow. Moreover, the flow fields are highly influenced by the presence and shape of the pulmonic stenosis; the most intense jets in the left pulmonary artery occur for a discrete pulmonic stenosis of 75%. The flow in the right pulmonary artery is nearly steady because it is damped down by the steady caval flow.

摘要

双向腔肺吻合术是一种用于治疗右心严重先天性畸形的外科技术。它通过将上腔静脉与未分隔的右肺动脉的上缘进行吻合来实现。利用双向腔肺吻合术的三维模型进行了瞬态模拟,以评估不同类型肺动脉狭窄(梗阻的形状和严重程度)的血流动力学。研究了具有不同横截面积减小值(60%和75%)的隧道样(瓣上)或离散(瓣膜)肺动脉狭窄模型,并与无狭窄模型进行了比较。计算基于有限元方法分析。结果表明,更严重的狭窄可导致流向左肺的血容量流量达到总肺血流量的70%。此外,流场受肺动脉狭窄的存在和形状的高度影响;左肺动脉中最强烈的射流出现在75%的离散肺动脉狭窄时。右肺动脉中的血流几乎是稳定的,因为它被稳定的腔静脉血流所衰减。

相似文献

1
Computational transient simulations with varying degree and shape of pulmonic stenosis in models of the bidirectional cavopulmonary anastomosis.在双向腔肺吻合模型中对不同程度和形状的肺动脉狭窄进行计算性瞬态模拟。
Med Eng Phys. 1997 Jun;19(4):394-403. doi: 10.1016/s1350-4533(96)00070-7.
2
Use of computational fluid dynamics in the design of surgical procedures: application to the study of competitive flows in cavo-pulmonary connections.计算流体动力学在外科手术设计中的应用:在腔肺连接中竞争性血流研究中的应用
J Thorac Cardiovasc Surg. 1996 Mar;111(3):502-13. doi: 10.1016/s0022-5223(96)70302-1.
3
A computational pulsatile model of the bidirectional cavopulmonary anastomosis: the influence of pulmonary forward flow.双向腔肺吻合术的计算脉动模型:肺前向血流的影响。
J Biomech Eng. 1996 Nov;118(4):520-8. doi: 10.1115/1.2796039.
4
Physiological rationale for a bidirectional cavopulmonary shunt. A versatile complement to the Fontan principle.双向腔肺分流的生理学原理。对Fontan原则的一种通用补充。
J Thorac Cardiovasc Surg. 1985 Sep;90(3):391-8.
5
The beneficial vortex and best spatial arrangement in total extracardiac cavopulmonary connection.全腔静脉-肺动脉连接术中的有益涡流和最佳空间排列
J Thorac Cardiovasc Surg. 2002 Sep;124(3):471-8. doi: 10.1067/mtc.2002.120349.
6
Doppler flow profiles in the right and left pulmonary artery in children with congenital heart disease and a bidirectional cavopulmonary shunt.
Pediatr Cardiol. 1994 Nov-Dec;15(6):302-7. doi: 10.1007/BF00798124.
7
Bidirectional superior cavopulmonary anastomosis improves mechanical efficiency in dilated atriopulmonary connections.双向上腔静脉-肺动脉吻合术可提高扩张型心房-肺动脉连接的机械效率。
J Thorac Cardiovasc Surg. 1999 Oct;118(4):681-91. doi: 10.1016/S0022-5223(99)70014-0.
8
Systemic venous collateral development after the bidirectional cavopulmonary anastomosis. Prevalence and predictors.双向腔肺吻合术后体循环静脉侧支循环的发育。患病率及预测因素。
J Am Coll Cardiol. 1998 Aug;32(2):502-8. doi: 10.1016/s0735-1097(98)00246-0.
9
Biventricular repair of hypoplastic right ventricle assisted by pulsatile bidirectional cavopulmonary anastomosis.搏动性双向腔肺吻合辅助下的右心室发育不全双心室修复术。
J Thorac Cardiovasc Surg. 1993 Jan;105(1):112-9.
10
Additional pulmonary blood flow has no adverse effect on outcome after bidirectional cavopulmonary anastomosis.额外的肺血流量对双向腔肺吻合术后的预后没有不良影响。
Ann Thorac Surg. 2005 Jan;79(1):29-36; discussion 36-7. doi: 10.1016/j.athoracsur.2004.06.002.

引用本文的文献

1
Computational fluid dynamics in paediatric cardiac surgery.小儿心脏手术中的计算流体动力学
Images Paediatr Cardiol. 2000 Jan;2(1):11-25.
2
Modeling the Fontan circulation: where we are and where we need to go.模拟Fontan循环:我们所处的位置以及我们需要前进的方向。
Pediatr Cardiol. 2008 Jan;29(1):3-12. doi: 10.1007/s00246-007-9104-0. Epub 2007 Oct 5.
3
Toward optimal hemodynamics: computer modeling of the Fontan circuit.迈向最佳血流动力学:Fontan循环的计算机建模
Pediatr Cardiol. 2007 Nov-Dec;28(6):477-81. doi: 10.1007/s00246-007-9009-y.