多种动物致病性支原体对氟喹诺酮类药物的敏感性比较。
Comparative susceptibilities of various animal-pathogenic mycoplasmas to fluoroquinolones.
作者信息
Hannan P C, Windsor G D, de Jong A, Schmeer N, Stegemann M
机构信息
Mycoplasma Experience Ltd., Reigate, Surrey, United Kingdom.
出版信息
Antimicrob Agents Chemother. 1997 Sep;41(9):2037-40. doi: 10.1128/AAC.41.9.2037.
Abstract
The in vitro activities of six antimicrobial agents were tested against 162 mycoplasma strains of eight species isolated from poultry and livestock at different geographic sites. Tiamulin was most active (MICs at which 90% of the isolates were inhibited [MIC90s], 0.025 to 0.25 microg/ml); enrofloxacin and danofloxacin had near equivalent activities (MIC90s, 0.05 to 1.0 microg/ml), but were much more active than flumequine (MIC90s, 1 to 50 microg/ml). The MIC90s of tylosin and oxytetracycline were 0.25 to > 100 microg/ml and 0.25 to 100 microg/ml, respectively.
摘要
对从不同地理位置的家禽和家畜中分离出的8个物种的162株支原体菌株，测试了6种抗菌剂的体外活性。泰妙菌素活性最强（90%分离株被抑制时的最低抑菌浓度[MIC90]，0.025至0.25微克/毫升）；恩诺沙星和达氟沙星活性相近（MIC90，0.05至1.0微克/毫升），但比氟甲喹活性强得多（MIC90，1至50微克/毫升）。泰乐菌素和土霉素的MIC90分别为0.25至>100微克/毫升和0.25至100微克/毫升。
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