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[缺氧条件下大脑非特异性激活和抑制系统的状态]

[State of non-specific activating and inhibitory systems of the brain under hypoxic conditions].

作者信息

Akopian N S, Baklavadzhian O G

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Sep-Oct;27(5):1061-7.

PMID:930402
Abstract

The functional state of the rabbit brain activating system was evaluated by the activation reaction, and the thalamic inhibitory system, by the recruiting response. At the initial phase of hypoxia, excitability of the activating system was enhanced, while at the same time the eugmenting phase of the recruiting response diminished and its inhibitory phase was prolonged. At the "altitude" of about 7000 m, against the background of a gradual weakening of the ascending activating influence of the reticular formation and the hypthalamus, the recruiting response assumed the form of regular; equally negative potentials, which testifies to the activie synchronizing influence of the inhibitory system. At a "rise" to 8500 m, against the background of slow synchronized EEG waves, in most cases there was no activation reaction to the stimulation of the reticular formation and hypothalamus. Neither was there any recruiting response to the stimulation of non-specific thalamic nuclei.

摘要

通过激活反应评估兔脑激活系统的功能状态,通过募集反应评估丘脑抑制系统的功能状态。在缺氧初期,激活系统的兴奋性增强,而与此同时,募集反应的增强期减弱,抑制期延长。在约7000米的“高度”时,在网状结构和下丘脑的上行激活影响逐渐减弱的背景下,募集反应呈现出规则的、同等负电位的形式,这证明了抑制系统的积极同步影响。在“上升”到8500米时,在脑电图缓慢同步波的背景下,大多数情况下,对网状结构和下丘脑的刺激没有激活反应。对丘脑非特异性核团的刺激也没有任何募集反应。

相似文献

1
[State of non-specific activating and inhibitory systems of the brain under hypoxic conditions].[缺氧条件下大脑非特异性激活和抑制系统的状态]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Sep-Oct;27(5):1061-7.
2
[Changes in the oxygen tension and bioelectrical activity of the brains of animals subjected to acute hypoxia].[急性缺氧动物脑氧分压及生物电活动的变化]
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[Effect of the hypothalamus and reticular formation on the cerebral cortex in hypoxic brain states].[下丘脑和网状结构在缺氧性脑状态下对大脑皮质的影响]
Fiziol Zh SSSR Im I M Sechenova. 1975 Oct;61(10):1524-30.
4
[EEG of rabbits in experimental encephalitis].[实验性脑炎家兔的脑电图]
Biull Eksp Biol Med. 1971 Oct;72(10):24-6.
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Fiziol Zh SSSR Im I M Sechenova. 1972 Jun;58(6):851-8.
6
[Electrical activity of the cortex and subcortical structures during the development of hypoxia due to blood loss].[失血导致缺氧发展过程中皮质及皮质下结构的电活动]
Biull Eksp Biol Med. 1978 Jun;85(6):658-61.
7
Preoptic hypnogenic area and reticular activating system.视前区促眠区和网状激活系统。
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8
[Properties of the thalamocortical nonspecific system].[丘脑皮质非特异性系统的特性]
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[Effect of acute hypoxia on specific and nonspecific brain systems in rabbits].[急性缺氧对家兔特异性和非特异性脑系统的影响]
Kosm Biol Aviakosm Med. 1979 Nov-Dec;13(6):53-7.