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[急性缺氧动物脑氧分压及生物电活动的变化]

[Changes in the oxygen tension and bioelectrical activity of the brains of animals subjected to acute hypoxia].

作者信息

Akopian N S, Baklavadzhian O G

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1975 Sep;61(9):1303-9.

PMID:1213192
Abstract

Simultaneous recording of oxygen tension (pO2) and bioelectrical activity led from different cerebral structures was made in rabbits and rats with implanted electrodes under conditions of acute hypoxia. Marked activation of the EEG as electrophysiological correlate of behavioural response was observed in rabbits only at the beginning of "ascent" and "descent". The EEG, respiration, and cardiac activity changes associated with the drop of PO2 in the brain tissue (activation of these parameters at the low "altitude" /2000-6000 m/ and their suppression at the maximal "altitudes" /8500 m/) were of approximately of the same character in both species.

摘要

在急性缺氧条件下,对植入电极的家兔和大鼠同时记录不同脑结构的氧分压(pO2)和生物电活动。仅在家兔“上升”和“下降”开始时观察到脑电图(EEG)明显激活,作为行为反应的电生理关联。脑组织中PO2下降相关的脑电图、呼吸和心脏活动变化(这些参数在低“海拔”/2000 - 6000米/时激活,在最大“海拔”/8500米/时抑制)在两个物种中大致相同。

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