Byg K E, Milman N, Clausen P P, Radulescu B
Medicinsk afdeling, Centralsygehuset i Naestved.
Ugeskr Laeger. 1997 Sep 1;159(36):5384-6.
Mycobacterium marinum is a rare cause of disseminated infection in man. The case report describes an 80-year-old woman, who had been treated with oral corticosteroids for bronchial asthma for 40 years, and in the same period had been swimming daily in swimming pools. At the first admission, the symptoms and clinical findings were interpreted as seronegative rheumatoid arthritis. After eight years of disease with recurrent infections of the skin, periarticular tissues and joints in the hands and one elbow, a biopsy specimen from an abscess showed granulomatous inflammation and acid fast bacilli. Culture for mycobacteria grew M. marinum. There was a severe, destructive monoarthritis in the right second metacarpophalangeal joint. The patient recovered completely on treatment with clarithromycin and doxycycline.
海分枝杆菌是人类播散性感染的罕见病因。该病例报告描述了一名80岁女性，她因支气管哮喘接受口服皮质类固醇治疗40年，在此期间每天都在游泳池游泳。首次入院时，症状和临床检查结果被诊断为血清阴性类风湿关节炎。在患病8年期间，手部和一个肘部的皮肤、关节周围组织和关节反复感染，脓肿活检标本显示肉芽肿性炎症和抗酸杆菌。分枝杆菌培养分离出海分枝杆菌。右第二掌指关节出现严重的破坏性单关节炎。患者接受克拉霉素和强力霉素治疗后完全康复。
