Yamazaki Y, Hayamizu F, Miyamoto S, Nakagami T, Tanaka C, Inui S
Department of Ophthalmology, Nihon University School of Medicine, Tokyo, Japan.
Jpn J Ophthalmol. 1997 Jul-Aug;41(4):260-7. doi: 10.1016/s0021-5155(97)00052-x.
One hundred thirty stereo photographs of optic discs in patients with normal tension glaucoma (NTG) were reviewed in order to identify characteristics of the three following types of NTG: focal ischemic, senile sclerotic, and generalized cup enlargement. Twenty patients in each group were selected. Focal ischemic patients were more frequently women, had a higher incidence of migraine, a relatively smaller disc size, and localized superior scotoma that often threatened fixation. Senile sclerotic patients were generally elderly, had a higher incidence of surgery under general anesthesia, had more ischemic heart disease or systemic hypertension, had a small rim area, and also had extensive peripapillary atrophy as well as combined diffuse and localized visual field defects. Generalized cup enlargement patients were younger, had a relatively larger disc size and a greater incidence of purely diffuse visual field loss. Results of our study suggest that the different characteristics of the groups are related to pathogenic mechanisms specific to each group.
