Smiddy W E, Pimentel S, Williams G A
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, FL, USA.
Ophthalmic Surg Lasers. 1997 Sep;28(9):713-7.
To evaluate the efficacy of performing surgical techniques for macular holes without using adjunctive additives.
A prospective study was completed of consecutive eyes treated for macular holes of 1 year or less duration that had not had previous vitreous surgery. The best-corrected visual acuity and hole flattening were determined.
Postoperative flattening of the hole was achieved in 39 (91%) of 43 eyes, with at least a 50% reduction of the minimum resolvable visual angle (3-line visual increase) in 65% of the eyes and a final vision of 20/40 or better in 40% of the eyes during the follow-up interval (mean 10.6 months).
The success rate of current macular hole surgical techniques suggests that adjunctive additives may not be necessary for most cases. Thus, new treatment modalities need to be evaluated with carefully controlled studies.
评估不使用辅助添加剂进行黄斑裂孔手术技术的疗效。
对连续治疗的病程在1年及以内且未曾接受过玻璃体手术的黄斑裂孔眼进行前瞻性研究。测定最佳矫正视力和裂孔闭合情况。
43眼中有39眼（91%）术后裂孔闭合，随访期间（平均10.6个月），65%的眼最小分辨视角至少降低50%（视力提高3行），40%的眼最终视力达到20/40或更好。
当前黄斑裂孔手术技术的成功率表明，大多数情况下可能无需辅助添加剂。因此，需要通过严格对照研究来评估新的治疗方式。
