Rauz S, Subramaniam S
Department of Ophthalmology, Charing Cross Hospital, London, United Kingdom.
Ophthalmic Surg Lasers. 1997 Sep;28(9):727-30.
To assess the necessary volume of local anesthetic with added hyaluronidase that must be infiltrated to the sub-Tenon's space to achieve complete eyelid akinesia.
Eighty-five consecutive patients were randomly assigned to two groups, receiving either 5 ml or 7 ml of local anesthetic to the sub-Tenon's space. Each patient was assessed clinically at 5 and 10 minutes for orbicularis oculi function. The anesthetic solution consisted of 5 ml of 2% lidocaine, 5 ml of 0.75% bupivacaine hydrochloride, and 1500 IU of hyaluronidase. A top-up of anesthetic infiltration was given in doses of 2 ml if excessive orbicularis muscle function persisted at 10 ml. Routine phacoemulsification surgery was performed, and, if necessary, a top-up of anesthetic was given on the table.
Complete eyelid akinesia was achieved in 7.5% (3 of 40) of the patients in the 5-ml group and in 93.3% (42 of 45) of the patients in the 7-ml group (P < .005). There was no effect for 57.5% (23 of 40) of the patients in the 5-ml group and for 2.2% (1 of 45) of the patients in the 7-ml group. A top-up of anesthetic was given in the anesthetic room to 40 patients, 37 of whom were in the 5-ml group, and a Van Lint block of the facial nerves was necessary for 1 patient from the 5-ml group. An on-the-table top-up of anesthesia was necessary for 3 patients (2 from the 5-ml group, 1 from the 7-ml group).
The addition of hyaluronidase promotes diffusion of sub-Tenon's anesthetic, resulting in effective akinesia of the orbicularis oculi. The infiltration of 7 ml of the anesthetic solution significantly improves the rate of eyelid akinesia.
评估必须注入球后间隙以实现完全眼睑运动不能所需添加透明质酸酶的局部麻醉剂的必要体积。
85例连续患者被随机分为两组,分别接受5毫升或7毫升局部麻醉剂注入球后间隙。在5分钟和10分钟时对每位患者的眼轮匝肌功能进行临床评估。麻醉溶液由5毫升2%利多卡因、5毫升0.75%盐酸布比卡因和1500国际单位透明质酸酶组成。如果在10分钟时眼轮匝肌功能持续过度,则以2毫升的剂量补充麻醉剂浸润。进行常规超声乳化手术,必要时在手术台上补充麻醉剂。
5毫升组7.5%(40例中的3例)患者和7毫升组93.3%(45例中的42例)患者实现了完全眼睑运动不能(P <.005)。5毫升组57.5%(40例中的23例)患者和7毫升组2.2%(45例中的1例)患者无效果。40例患者在麻醉室补充了麻醉剂,其中37例在5毫升组,5毫升组有1例患者需要进行面神经范林特阻滞。3例患者(2例来自5毫升组,1例来自7毫升组)在手术台上需要补充麻醉。
添加透明质酸酶可促进球后麻醉剂的扩散,导致眼轮匝肌有效运动不能。注入7毫升麻醉溶液可显著提高眼睑运动不能的发生率。