Aldenkamp A P, Mulder O G
Department of Behavioral Research and Psychological Services, Kempenhaeghe Heeze, The Netherlands.
Seizure. 1997 Aug;6(4):275-82. doi: 10.1016/s1059-1311(97)80074-x.
The diagnosis of pseudo-epileptic seizures (PES) is confirmed in 7-10% of the patients that are considered to suffer from 'refractory epilepsies'. As yet no consistent model is available to explain the development of PES in individual patients. This open non-randomized clinical study aimed at assessing behavioural mechanisms that trigger PES, independent of the underlying personality characteristics. Twenty-four patients with PES were compared with pairwise matched patients that suffered exclusively from genuine epileptic seizures (ES). The patients were assessed with two personality inventories that measured potential important behavioural mechanisms: the 19 PF-form B of the Cattell IPAT Anxiety Scale and the Dutch ABV-scale, largely based on Eysenck's Maudsley Personality Inventory. This assessment was complemented with individual history taking and psychiatric examination. The results are presented in a model in which three factors are involved that have a combined effect on the development of PES in individual patients: personality disorders (of heterogeneous origin), the behavioural mechanism of somatization and a familiarity with epilepsy as a modifying factor.
在被认为患有“难治性癫痫”的患者中，7%至10%被确诊为假性癫痫发作（PES）。目前尚无统一的模型来解释个体患者中PES的发生发展。这项开放性非随机临床研究旨在评估引发PES的行为机制，而不考虑潜在的人格特征。将24例PES患者与仅患有真性癫痫发作（ES）的配对患者进行比较。使用两个人格量表对患者进行评估，这两个人格量表测量了潜在的重要行为机制：卡特尔IPAT焦虑量表的19 PF-form B和主要基于艾森克莫兹利人格量表的荷兰ABV量表。通过个人病史采集和精神科检查对该评估进行补充。结果呈现于一个模型中，该模型涉及三个因素，它们对个体患者中PES的发生发展具有综合影响：（起源各异的）人格障碍、躯体化行为机制以及作为调节因素的对癫痫的熟悉程度。
