Watanabe Y, Yamada S, Nagai A, Takayama T, Hirata K, Bunai Y, Ohya I
Department of Legal Medicine, Gifu University School of Medicine, Japan.
J Forensic Sci. 1997 Sep;42(5):911-3.
Population studies on the five loci LDLR, GYPA, HBGG, D7S8, and GC (PM loci) were carried out in a sample of 366 unrelated Japanese individuals living in Gifu Prefecture (central region of Japan) using the AmpliType PM PCR Amplification and Typing kit (Perkin Elmer). For all loci, no significant deviations from Hardy-Weinberg equilibrium could be found in our Japanese population sample. The combined mean exclusion chance and power of discrimination for the PM loci were 0.68 and 0.993, respectively. The Japanese and Chinese population data were similar for the all loci. The Japanese and Korean population data were similar for all loci other than D7S8. Significant differences were observed between the Japanese population data and the 16 other population data compared for 3 loci or more.
利用AmpliType PM PCR扩增及分型试剂盒（珀金埃尔默公司），对居住在岐阜县（日本中部地区）的366名无亲缘关系的日本人样本进行了低密度脂蛋白受体（LDLR）、血型糖蛋白A（GYPA）、β-血红蛋白基因（HBGG）、D7S8及组特异性成分（GC）这五个基因座（PM基因座）的群体研究。对于所有基因座，在我们的日本人群样本中均未发现与哈迪-温伯格平衡有显著偏差。PM基因座的平均联合排除概率和鉴别能力分别为0.68和0.993。所有基因座的日本和中国人群数据相似。除D7S8外，所有基因座的日本和韩国人群数据相似。在比较3个或更多基因座时，观察到日本人群数据与其他16个群体数据之间存在显著差异。
