Sukhorebraia L A, Pesnia V V, Markova E D, Dukarskiĭ F G
Zh Nevropatol Psikhiatr Im S S Korsakova. 1977;77(10):1463-6.
The authors accomplished a study of the concentration of free aminoacids in the blood and urine of patients with torsion dystonia by means of a high voltage electrophoresis with a subsequent ascending chromatography. A division of such patients into 2 clinical forms is reflected in the found concentration of free aminoacids in the blood and urine. In patients with the rigid form along with generalized hyperacidemia there are also significant changes in the concentration of aminoacids of the aromatic line. In the group of patients with the hyperkinetic form the most significant changes were seen for valine, methionine, serine, alanine and cystine, while as the spectrum of aminoacids of the aromatic line is practically unchanged. The found changes in the spectrum of free aminoacids are most likely connected with disorders of catecholamine metabolism in torsion dystonia.
