通过序列标签位点分析揭示的105个新的潜在黑腹果蝇基因。

One-hundred and five new potential Drosophila melanogaster genes revealed through STS analysis.

作者信息

Louis C, Madueño E, Modolell J, Omar M M, Papagiannakis G, Saunders R D, Savakis C, Sidén-Kiamos I, Spanos L, Topalis P, Zhang Y Q, Ashburner M, Benos P, Bolshakov V N, Deak P, Glover D M, Herrmann S, Kafatos F C

机构信息

Institute of Molecular Biology and Biotechnology, FORTH, Heraklion, Crete, Greece.

出版信息

Gene. 1997 Aug 22;195(2):187-93. doi: 10.1016/s0378-1119(97)00138-8.

DOI:10.1016/s0378-1119(97)00138-8

PMID:9305763

Abstract

Complementation analysis had suggested that the Drosophila melanogaster genome contains approximately 5000 genes, but it is now generally accepted that the actual number is several times as high. We report here an analysis of 1788 anonymous sequence tagged sites (STSs) from the European Drosophila Genome Project (EDGP), totalling 463 kb. The data reveal a substantial number of previously undescribed potential genes, amounting to 6.1% of the number of Drosophila genes already in the sequence databases.

摘要

互补分析曾表明，黑腹果蝇基因组大约包含5000个基因，但现在人们普遍认为实际数量要高出几倍。我们在此报告对来自欧洲果蝇基因组计划（EDGP）的1788个匿名序列标签位点（STS）的分析，这些位点总计463 kb。数据揭示了大量此前未被描述的潜在基因，其数量占到了序列数据库中已有果蝇基因数量的6.1%。