通过混合细胞凝集反应对一例ABO血型不相容输血病例中的血管内凝集进行免疫组织学分析。
Immunohistological analysis of intravascular agglutination in a case of ABO incompatible blood transfusion by means of mixed cell agglutination reaction.
作者信息
Tokoro Y, Chang S, Nagai T, Ishiyama I
出版信息
Acta Pathol Jpn. 1977 Sep;27(5):729-38. doi: 10.1111/j.1440-1827.1977.tb00188.x.
Applicability of the mixed cell agglutination reaction (MCAR of Davidsohn) in histological examination was tested in a case of ABO incompatible blood transfusion, who had died of severe head injury two days after an accident. Massively disseminated intravascular aggregation of erythrocytes was identified as immune agglutination by the modified method of MCAR (ISHIYAMA & OKADA) with precise knowledge of topographic isoantigen localization in tissues. The immune specific agglutination mimics intravascular changes such as hyperemia, stagnation and hemorrhage derived from various circulatory disturbances obtained in routine autopsy materials.
在一名因事故两天后死于严重头部损伤的ABO血型不相容输血病例中，对混合细胞凝集反应（Davidsohn的MCAR）在组织学检查中的适用性进行了测试。通过改良的MCAR方法（ISHIYAMA & OKADA），并精确了解组织中局部同种抗原的定位，将大量弥漫性血管内红细胞聚集鉴定为免疫凝集。这种免疫特异性凝集模拟了常规尸检材料中因各种循环障碍而出现的血管内变化，如充血、淤血和出血。
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