Fujikawa T, Nishimura S, Matsusue S, Takeda H
Department of Abdominal Surgery, Tenri Hospital, Nara, Japan.
Surg Today. 1997;27(8):769-72. doi: 10.1007/BF02384995.
We report herein the case of a women receiving tamoxifen therapy for breast cancer who developed vaginal bleeding, subsequently found to be caused by unusual endometrial polyps. Upon presentation, ultrasonography and magnetic resonance imaging (MRI) demonstrated a tumor within the uterus. A hysterectomy was performed, and macroscopic examination showed polyp-like lesions of the uterus. Histologically, these polyps demonstrated cystically dilated glands and stromal proliferation, and were diagnosed as endometrial polyps. Although tamoxifen has few side effects, any signs or symptoms of gynecological abnormalities should be carefully evaluated in patients on long-term tamoxifen therapy.
我们在此报告一例接受他莫昔芬治疗乳腺癌的女性病例，该患者出现阴道出血，随后发现是由异常子宫内膜息肉引起的。就诊时，超声检查和磁共振成像（MRI）显示子宫内有一个肿瘤。进行了子宫切除术，宏观检查显示子宫有息肉样病变。组织学上，这些息肉表现为腺体囊性扩张和间质增生，被诊断为子宫内膜息肉。尽管他莫昔芬副作用较少，但长期接受他莫昔芬治疗的患者若出现任何妇科异常的体征或症状，都应仔细评估。
