大鼠六氯丁二烯两年慢性毒性研究结果。
Results of a two year chronic toxicity study with hexachlorobutadiene in rats.
作者信息
Kociba R J, Keyes D G, Jersey G C, Ballard J J, Dittenber D A, Quast J F, Wade C E, Humiston C G, Schwetz B A
出版信息
Am Ind Hyg Assoc J. 1977 Nov;38(11):589-602. doi: 10.1080/00028897708984403.
PMID:930808
Abstract
Lifetime ingestion by rats of 0.2 mg/kg/day of hexachlorobutadiene caused no discernible ill effects. Slight degrees of primarily renal toxicity occurred with 2 mg/kg/day; 20 mg/kg/day caused multiple toxic effects, including renal tubular neoplasms.
摘要
大鼠终生每天摄入0.2毫克/千克的六氯丁二烯未产生明显不良影响。每天摄入2毫克/千克会出现轻微程度的主要是肾脏毒性；每天摄入20毫克/千克会导致多种毒性作用，包括肾小管肿瘤。
Zotero 插件