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利用线扫描 Carr-Purcell-Meiboom-Gill 质子光谱成像技术对体内骨髓脂质进行表征。

In vivo bone marrow lipid characterization with line scan Carr-Purcell-Meiboom-Gill proton spectroscopic imaging.

作者信息

Mulkern R V, Meng J, Bowers J L, Oshio K, Zuo C, Li H, Kraft R A, Williamson D S, Jaramillo D

机构信息

Department of Radiology, Children's Hospital, Boston, MA, USA.

出版信息

Magn Reson Imaging. 1997;15(7):823-37. doi: 10.1016/s0730-725x(97)00134-3.

DOI:10.1016/s0730-725x(97)00134-3
PMID:9309613
Abstract

Line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging sequences have been used to extract lipid chemical composition indices in healthy adult bone marrow in the knee at 1.5 T. Since several spectroscopic echo readouts follow each excitation, the information acquired reflects a balance between spectral T2 decay processes and spectral resolution. To examine this balance in detail, data sets with two different echo spacings and spectral resolutions have been acquired to compare the information available from each in studies of bone marrow. Oils for which high field (7 T) proton spectra were recorded were used to evaluate the accuracy of lipid chemical composition indices extracted from the line scan Carr-Purcell-Meiboom-Gill spectroscopic imaging methods at 1.5 T. The extension of the method to fast spectroscopic imaging of bone marrow with multiple echoes is demonstrated.

摘要

线扫描Carr-Purcell-Meiboom-Gill光谱成像序列已被用于在1.5T场强下提取健康成年膝关节骨髓中的脂质化学成分指数。由于每次激发后会有多个光谱回波读出,所获取的信息反映了光谱T2衰减过程和光谱分辨率之间的平衡。为了详细研究这种平衡,已采集了具有两种不同回波间隔和光谱分辨率的数据集,以比较在骨髓研究中每种数据集可获得的信息。使用记录了高场(7T)质子光谱的油来评估从1.5T场强下的线扫描Carr-Purcell-Meiboom-Gill光谱成像方法中提取的脂质化学成分指数的准确性。展示了该方法扩展到具有多个回波的骨髓快速光谱成像。

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