Moghissi K S, Gruber J S, Evans S, Yanez J
Am J Obstet Gynecol. 1977 Dec 15;129(8):909-15. doi: 10.1016/0002-9378(77)90523-3.
Homologous artificial insemination (AIH), with the use of a split-ejaculate technique, was performed in 62 couples following a complete infertility investigation. Fifty per cent of all men had a sperm count less than 50 million per milliliter and 80 per cent had sperm motility less than 50 per cent. More important, 85 per cent of the initial semen samples had greater than 40 per cent abnormal forms and liquefaction was delayed beyond 20 minutes in 67 per cent of specimen. The pregnancy rate for the 28 women who underwent the prescribed course of six or more inseminations was 46.4 per cent, for the group of 60 who received split-ejaculate AIH, 21.6 per cent; and for the entire group of 62 couples, 24.2 per cent. In the split-ejaculate group 50 per cent of the pregnancies resulted in first-trimester abortions. It is suggested that the pregnancy wastage in these couples might be due to male factors.
在对62对夫妇进行全面不孕检查后，采用分段射精技术进行了同源人工授精（AIH）。所有男性中，50%的精子计数低于每毫升5000万，80%的精子活力低于50%。更重要的是，85%的初始精液样本畸形率超过40%，67%的样本液化延迟超过20分钟。接受规定的六次或更多次授精疗程的28名女性的妊娠率为46.4%，接受分段射精AIH的60名女性的妊娠率为21.6%；62对夫妇的总妊娠率为24.2%。在分段射精组中，50%的妊娠导致孕早期流产。提示这些夫妇的妊娠丢失可能是男性因素所致。
