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职业性铅暴露对人体免疫球蛋白浓度及细胞免疫功能的影响

[Effect of occupational lead exposure on immunoglobulin concentration and cellular immune function in man].

作者信息

Castillo Méndez A, Rodríguez Díaz T, León Lobeck A, Gravalosa Cruz A J

机构信息

Sección de alergia e inmunología clínica, Instituto de Medicina del Trabajo, ciudad de La Habana, Cuba.

出版信息

Rev Alerg. 1993 Mar-Apr;40(2):33-6.

PMID:9312331
Abstract

The evaluation of immunological conditions of 14 workers occupationally exposed to lead and the comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant decrease in the formation for rosette in relation to the control group.

摘要

本研究旨在评估14名职业性接触铅的工人的免疫状况,并将这些结果与年龄和性别相似的非接触对照组的结果进行比较。测定了血铅的平均值。接触铅的工人血铅平均值为46.9微克/分升,而对照组为10.9微克/分升。发现接触铅的工人血铅浓度升高时免疫球蛋白水平下降。还发现与对照组相比,玫瑰花结形成显著减少。

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