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[通过化学发光法检测中性粒细胞的吞噬活性以及铅的职业暴露]

[The phagocytic activity of the neutrophilic granulocytes via chemoluminescence and occupational exposure to lead].

作者信息

L'Abbate N, Rana F, Cassano F, Vaira A, Specchia G, Liso V

机构信息

Istituto di Medicina del Lavoro, Università di Bari.

出版信息

G Ital Med Lav. 1989 Nov;11(6):279-82.

PMID:2562749
Abstract

The lead interference on the immunological activity is the aim of this survey. Therefore, it was examined the phagocytic function of the PMN cells on a group of 20 subjects occupationally exposed to the toxic and on 20 other assigned to the control group using the chemoluminescent assay. In both groups it was determined the biologicals parameters of exposure to the toxic. It was evident a statistically significant decrease of the average values in the exposed group compared to the control group, even if it wasn't directly correlated with the exposure biological indicators.

摘要

本研究旨在调查铅对免疫活性的干扰。因此,采用化学发光分析法,对20名职业性接触毒物的受试者和另外20名作为对照组的受试者的中性粒细胞吞噬功能进行了检测。在两组中均测定了毒物暴露的生物学参数。与对照组相比,暴露组的平均值出现了具有统计学意义的显著下降,即使这与暴露生物学指标并无直接关联。

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