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[创伤性脊髓损伤的预后。临床及电生理检查结果的意义]

[Prognosis of traumatic spinal cord lesions. Significance of clinical and electrophysiological findings].

作者信息

Curt A, Dietz V

机构信息

Schweizerisches Paraplegikerzentrum, Universitätsklinik Balgrist, Zürich.

出版信息

Nervenarzt. 1997 Jun;68(6):485-95. doi: 10.1007/s001150050151.

DOI:10.1007/s001150050151
PMID:9312682
Abstract

The clinical examination of patients with spinal cord injury can be supplemented by electrophysiological techniques (somatosensory-evoked potentials (SSEP), motor-evoked potentials (MEP), electroneurography) to assess the extent and severity of a spinal cord injury. As essential advantage of these techniques in comparison with the clinical examination is that they can be reliably applied even in uncooperative patients. These techniques allow an early prognosis of the functional deficit in patients with acute spinal cord injury. Recordings of tibial nerve SSEP and MEP of the anterior tibial muscle allow to predict the outcome of ambulatory capacity, while recordings of pudendal nerve SSEP allow prognosis of the bladder function to be assessed. In tetraplegic patients median and ulnar nerve SSEP and MEP of the abductor digiti minimi muscle can indicate the development of hand function. Electroneurography allows to differentiate between the proportion of peripheral and central nervous lesions underlying the muscle paresis. This is of prognostic value with regard to the development of muscle tone and consequently for planning therapy. The electrophysiological examinations are of complementary value in the diagnostic assessment of spinal cord lesions, in the prediction of functional outcome, and in monitoring the course of neurological deficits. This is helpful for planning and selection of appropriate therapeutic approaches (e.g. functional electrical stimulation, application of botulinum toxin, splinting procedures) within the rehabilitation programme.

摘要

脊髓损伤患者的临床检查可通过电生理技术(体感诱发电位(SSEP)、运动诱发电位(MEP)、神经电图)进行补充,以评估脊髓损伤的程度和严重程度。与临床检查相比,这些技术的一个重要优势是即使在不合作的患者中也能可靠应用。这些技术可以对急性脊髓损伤患者的功能缺陷进行早期预后评估。记录胫神经SSEP和胫前肌的MEP可以预测步行能力的结果,而记录阴部神经SSEP可以评估膀胱功能的预后。在四肢瘫痪患者中,正中神经和尺神经SSEP以及小指展肌的MEP可以指示手部功能的发展。神经电图可以区分肌肉麻痹背后的周围神经和中枢神经病变的比例。这对于肌张力的发展以及因此对于治疗计划具有预后价值。电生理检查在脊髓损伤的诊断评估、功能结果预测以及监测神经功能缺损的过程中具有补充价值。这有助于在康复计划中规划和选择合适的治疗方法(例如功能性电刺激、肉毒杆菌毒素应用、夹板固定程序)。

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