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肝切除在双侧肝内胆管结石手术中的作用。

Role of hepatic resection in surgery for bilateral intrahepatic stones.

作者信息

Chen M F, Jan Y Y, Wang C S, Hwang T L, Jeng L B, Chen S C, Chao T C

机构信息

Department of Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan.

出版信息

Br J Surg. 1997 Sep;84(9):1229-32.

PMID:9313699
Abstract

BACKGROUND

Hepatic resection is the treatment of choice for unilateral intrahepatic stones. The availability of the flexible choledochoscope has greatly changed the management of intrahepatic stones. Little has been reported regarding hepatic resection for bilateral intrahepatic stones.

METHODS

Fifty-nine (15.1 per cent) of 392 patients with bilateral intrahepatic stones underwent hepatic resection. The indications and results were reported. Surgical outcome and long-term follow-up were analysed, and results were compared with those in patients not undergoing hepatectomy.

RESULTS

Fifty-nine patients underwent hepatic resection because of destruction of the left liver by repeated infection (n = 40), multiple cholangitic liver abscesses (n = 18) or associated intrahepatic cholangiocarcinoma (n = 1). The hospital mortality rate was 1.7 per cent. The majority of complications were wound infection (9 per cent), haematobilia (5 per cent) and biliary fistula (3 per cent). The incidence of residual stones after surgery was 60 per cent. One year after postoperative choledochoscopic stone extraction, the rate of complete stone clearance was 84 per cent. In patients who did not have hepatectomy the respective rates were 90.1 and 52.9 per cent. The recurrence rate for stones in the hepatectomy and no-hepatectomy groups was 12 and 33.0 per cent respectively.

CONCLUSIONS

Compared with patients not undergoing hepatectomy, those having hepatic resection had similar operative risks, fewer residual stones and a low incidence of recurrent stones (P < 0.05).

摘要

背景

肝切除术是治疗单侧肝内胆管结石的首选方法。可弯曲胆道镜的应用极大地改变了肝内胆管结石的治疗方式。关于双侧肝内胆管结石肝切除术的报道较少。

方法

392例双侧肝内胆管结石患者中有59例(15.1%)接受了肝切除术。报告了手术指征和结果。分析了手术结果和长期随访情况,并将结果与未接受肝切除术的患者进行了比较。

结果

59例患者因反复感染导致左肝破坏(n = 40)、多发性胆管性肝脓肿(n = 18)或合并肝内胆管癌(n = 1)而接受肝切除术。医院死亡率为1.7%。大多数并发症为伤口感染(9%)、胆道出血(5%)和胆瘘(3%)。术后残余结石发生率为60%。术后经胆道镜取石1年后,结石完全清除率为84%。未接受肝切除术的患者相应比例分别为90.1%和52.9%。肝切除术组和未行肝切除术组结石复发率分别为12%和33.0%。

结论

与未接受肝切除术的患者相比,接受肝切除术的患者手术风险相似,残余结石较少,结石复发率低(P < 0.05)。

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