Curiel R V, Laurienzo J M, Unger E F, Panza J A
Cardiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Am J Cardiol. 1997 Sep 15;80(6):783-6. doi: 10.1016/s0002-9149(97)00517-1.
Forty-four patients with coronary artery disease and left ventricular dysfunction underwent transesophageal echocardiography with dobutamine infusion to investigate the relation between basal contractile function and inotropic reserve. No significant relation was observed between basal percent systolic thickening or diastolic thickness and the maximum increase in contractile function in response to dobutamine, thus emphasizing the heterogenity of the mechanisms by which coronary stenoses may affect contraction at rest and inotropic reserve in these patients.
44例患有冠状动脉疾病和左心室功能障碍的患者接受了经食管超声心动图检查,并静脉输注多巴酚丁胺,以研究基础收缩功能与变力性储备之间的关系。未观察到基础收缩期增厚百分比或舒张期厚度与多巴酚丁胺刺激后收缩功能的最大增加之间存在显著关系,从而强调了冠状动脉狭窄影响这些患者静息收缩和变力性储备的机制的异质性。