Ziv G
Isr J Med Sci. 1976 Mar;12(3):260-3.
The rates at which ampicillin, amoxycillin, metampicillin, hetacillin, and pivampicillin are absorbed from the bovine udder were compared, with the absorption rate of (14C)urea as reference. Straight-line semilogarithmic plots of the percentage of unabsorbed drug against time were obtained, suggesting first-order kinetics for the absorption process. Ampicillin, metampicillin and hetacillin were most slowly absorbed. Amoxycillin was absorbed twice as fast as ampicillin. Pivampicillin was absorbed most rapidly-at more than three times the rate of ampicillin.
比较了氨苄西林、阿莫西林、美坦西林、海他西林和匹氨西林从牛乳房的吸收速率，并以（14C）尿素的吸收速率作为参考。得到了未吸收药物百分比对时间的直线半对数图，表明吸收过程符合一级动力学。氨苄西林、美坦西林和海他西林吸收最慢。阿莫西林的吸收速度是氨苄西林的两倍。匹氨西林吸收最快，速度超过氨苄西林的三倍。
