[原发性硬化性胆管炎的罕见初始表现及鉴别诊断]
[Rare initial manifestation and differential diagnosis of primary sclerosing cholangitis].
作者信息
Rehermann B, Klugewitz K, Seifert U, Böker K H, Wagner S, Manns M P
机构信息
Abteilung Gastroenterologie und Hepatologie, Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule Hannover.
出版信息
Med Klin (Munich). 1997 Jul 15;92(7):452-6. doi: 10.1007/BF03042580.
BACKGROUND
Primary sclerosing cholangitis is most often diagnosed in middle-aged men who are suffering from inflammatory bowel diseases.
CASE REPORT
A young, previously healthy woman presents with icterus of acute onset, high transaminases and positive hepatitis B virus serology. Ultrasound and nuclear magnetic resonance images demonstrate multiple liver tumors. After acute viral hepatitis as well as primary or secondary malignant liver tumors have been excluded as underlying diseases, diagnosis of primary sclerosing cholangitis is made.
CONCLUSION
Differential diagnosis of primary sclerosing cholangitis should also be considered in cases with untypical primary presentation.
背景
原发性硬化性胆管炎最常诊断于患有炎症性肠病的中年男性。
病例报告
一名年轻、既往健康的女性出现急性发作的黄疸、转氨酶升高及乙肝病毒血清学阳性。超声和核磁共振成像显示肝脏有多个肿瘤。在排除急性病毒性肝炎以及原发性或继发性肝脏恶性肿瘤作为潜在疾病后，诊断为原发性硬化性胆管炎。
结论
对于非典型首发表现的病例，也应考虑原发性硬化性胆管炎的鉴别诊断。
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