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[脂肪乳化。关于超声作用、穿刺部位及脂肪组织的组织学研究]

[Lipoemulsification. A histological study on the action of ultrasound, access site and adipose tissue].

作者信息

Palmieri B, Bosio P, Catania N, Criscuolo M, Gozzi G

机构信息

Cattedra di Semeiotica Chirurgica, Università degli Studi, Modena.

出版信息

Minerva Chir. 1997 Jun;52(6):795-800.

PMID:9324664
Abstract

A new mini-invasive technique for the lysis of subcutaneous adipose tissue has emerged in recent years. This directly applies ultrasounds to the tissue by titanium probes. Ultrasounds act on parenchyma tissues, saving the structure and integrity of the blood vessels. Our study show histological features of the subcutaneous adipose tissue evolution just ultrasound-treated up to 30 days after surgery. Five obese female patients underwent the treatment by anesthesia. Before surgery the sites to treat were topically injected with sterile, hypotonic, apyrogen saline solution added with adrenaline, Biopsies have been taken intraoperatively from the border cutis of the holes made for the introduction of the titanium probes and from the subcutaneous adipose tissue. Biopsies have also been taken during a follow-up at 2, 5, 15 and 30 days postoperatively. Drains were positioned in the treated sites for at least 72 hours. The same sites were sutured so at to make later follow-up biopsies easier. Histological specimens were considered according to three dying methods: eosin-haematoxylin, Gomori and acetic orcein. We observed, as a confirmation the safety of the adipose tissue blood vessels, and the substitution of the destroyed adipose tissue with a microfibrillar connective tissue not subject to a sclerogenic evolution.

摘要

近年来出现了一种用于皮下脂肪组织溶解的新型微创技术。该技术通过钛探针将超声波直接作用于组织。超声波作用于实质组织,保留血管的结构和完整性。我们的研究展示了术后30天内接受超声治疗的皮下脂肪组织演变的组织学特征。五名肥胖女性患者接受了麻醉下的治疗。手术前,在治疗部位局部注射添加了肾上腺素的无菌、低渗、无热原盐溶液。术中从用于插入钛探针的孔的皮肤边缘以及皮下脂肪组织中获取活检样本。术后第2天、第5天、第15天和第30天随访时也进行了活检。在治疗部位放置引流管至少72小时。对相同部位进行缝合,以便后续更容易进行活检。根据苏木精-伊红染色、Gomori染色和醋酸地衣红染色三种染色方法对组织学标本进行分析。我们观察到,作为脂肪组织血管安全性的佐证,被破坏的脂肪组织被一种不会发生硬化演变的微纤维结缔组织所替代。

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