Hernández-Silverio González N, Bañares Baudet F, Gutiérrez Hernández P, Rodríguez P
Servicio de Urología, Hospital Universitario de Canarias, Tenerife.
Actas Urol Esp. 1997 Mar;21(3):260-3.
Until very recently, bilateral renal cell carcinoma was considered to be of very poor prognosis due to the poor results obtained with either radiotherapy or chemotherapy, which were completely ineffective in this type of tumours. In 1952, Krumbach performed the first radical nephrectomy and partial nephrectomy to a patient with bilateral synchronic renal cell carcinoma. This aggressive approach to bilateral renal cell carcinoma definitely changed the prognosis of these patients. Other authors with broad series of patients have clearly demonstrated that aggressive treatment of these tumours is the only approach that can offer patients a life opportunity with a significant 5-year survival ranging between 60-77.8% from the time of surgery.
直到最近，双侧肾细胞癌都被认为预后极差，因为放疗或化疗效果不佳，对这类肿瘤完全无效。1952年，克伦巴赫对一名双侧同步性肾细胞癌患者进行了首例根治性肾切除术和部分肾切除术。这种对双侧肾细胞癌的积极治疗方法无疑改变了这些患者的预后。其他拥有大量病例的作者清楚地表明，积极治疗这些肿瘤是唯一能为患者提供生存机会的方法，从手术时起5年生存率显著，在60%至77.8%之间。
